Research progression of ?-SYN in Cancer
- VernacularTitle:?-突触核蛋白与肿瘤的关系
- Author:
jian-ping, GUO
;
lin, MENG
- Publication Type:Journal Article
- Keywords:
?-SYN;
Breast neoplasms;
Metastasis;
Tumor marker
- From:
Journal of International Oncology
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
?-Synuclein (?-SYN ) .previously identified as a breast cancer specific gene, has a wildly tumor expression profile mainly in advanced stage. As a special chaperone,?- SYN stimulates the proliferation and metastasis of tumor cells through interacting with estrogen receptor and (or) BubR1. Meanwhile, it is also detectable in the serum or urine from tumor patients, which indicates that?- SYN could be potential as a tumor marker for diagnosis and prognosis.
