Research advancement on mechanism of dorsal root ganglia neurons apoptosis induced by platinum-based drug
- VernacularTitle:铂类制剂致后根神经节神经元凋亡机制
- Author:
kai, LI
;
ting, TIAN
- Publication Type:Journal Article
- Keywords:
Platinum compounds;
Neurons;
Apoptosis
- From:
Journal of International Oncology
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Cisplatin,carpolatin and oxaliplatin are platinum-based drugs that are widely used in cancer chemotherapy. Peripheral neuropathy is major dose-limiting side effect of platinum-based drug. Accordingly, this side effect restrict its clinic application. This review will focus on the research advancement on the mechanism of dorsal root ganglia neurons apoptosis in cellular and molecular biology.
