Nucleic acid aptamers and their applications in the diagnosis and treatment of tumor
- VernacularTitle:核酸适配子及其在肿瘤诊断与治疗中的应用
- Author:
bei, ZHANG
;
fang-yu, WU
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Diagnosis;
Therapy;
Nucleic acid aptamers
- From:
Journal of International Oncology
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Nucleic acid aptamers are ligands with high specificity and affinity for their targets, which are screened from large oligonucleotide pools by the SELEX technology. Their characteristics are superior to antibodies in many aspects, which make them important in the research of recognition of molecules. They can be used to determine the levels and inhibit the bioactivity of their targets. There're broad application prospects for aptamers in the diagnosis and treatment of tumor.