Research Progress of Activated Protein C
- VernacularTitle:活化蛋白C研究进展
- Author:
Ai-ai, DENG
;
Yi, QU
;
De-zhi, MU
- Publication Type:Journal Article
- Keywords:
activated protein C;
anticoagulantion;
anti-apoptosis;
neuron
- From:Journal of Applied Clinical Pediatrics
2006;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
Activated protein C(APC)is generated through hydrolysis of protein C by thrombin-thrombomodulin complex.APC has been proved to play different roles in many human diseases,such as anticoagulant,antiinflammatory,profibr-inolysis,antiapoptotic and endothelial cytoprotective activities.In this review,the research progress of the functions of APC and related diseases,especially the neural protective roles of APC in central nervous system were summarized.