Endoplasmic Reticulum Stress and Atherosclerosis
- VernacularTitle:内质网应激与动脉粥样硬化
- Author:
jing, DING
;
chao-mei, ZENG
;
jun-bao, DU
- Publication Type:Journal Article
- Keywords:
endoplasmic reticulum stress;
unfolded protein response;
signaling pathway;
atherosclerosis;
endothelial cell;
macrophage;
smooth muscle cell
- From:Journal of Applied Clinical Pediatrics
2006;0(13):-
- CountryChina
- Language:Chinese
-
Abstract:
Endoplasmic reticulum stress is another kind of sub-cell level stress which is discovered after nuclear stress and mitochond-rial stress.Endothelial cells,macrophages and smooth muscle cells play important roles in the formation of atherosclerosis.Endoplasmic reticulum stress participate the occurrence and development of atherosclerosis by regulating the inflammatory response,lipid metabolism and apoptosis of the above cells.
