Application of Gene Chip in Ischemic Brain Damage
- VernacularTitle:基因芯片技术在缺血性脑损伤研究中的应用
- Author:
jiao, LI
;
yi, QU
;
de-zhi, MU
- Publication Type:Journal Article
- Keywords:
gene chip;
ischemic brain damage;
pathogenesis
- From:Journal of Applied Clinical Pediatrics
2004;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
To understand the present application of gene chip in ischemic brain damage,investigate the application value and the future trends of gene chip technology,the literatures on the application of gene chip in the research of all kinds of ischemic brain damage in the database including MEDLINE,EMBASE,CNKI and VIP were reviewed and comprehensively analyzed.Literatures showed that many differential expressed genes including the significant regulating genes in the pathomechanism and some new neuroprotective genes were found during the application in the research of brain damage including global ischemia,focal cerebral ischemia,and hypoxic ischemic brain damage.Therefore,gene chip has manifested its great application value in the research of ischemic brain damage and deserves a further investigation.