Study Progress of Biological Function of Hepatitis B Virus X Protein and Signal Transduction
- VernacularTitle:乙型肝炎病毒X蛋白生物学作用及信号转导的研究进展
- Author:
hong-zhu, LU
;
qi-hong, FAN
- Publication Type:Journal Article
- Keywords:
hepatitis B virus;
X protein;
signal transduction;
heptocellular carcinoma;
transactivation
- From:Journal of Applied Clinical Pediatrics
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis B virus X protein(HBx) has a wide range of biological effects.It not only play important roles in the replication of the virus,but also in infects host cell proliferation and apoptosis,as well as the incidence of hepatocellular carcinoma.HBx trans-activation has a broad regulatory role in the virus itself and host genes.HBx,by interfering with multiple signaling pathways,affected a variety of biological characteristics of the host cell.
