Study Progress of Henoch-Schonlein Purpura Associated with Antiphospholipid Syndrome
- VernacularTitle:过敏性紫癜并抗磷脂综合征研究进展
- Author:
hong-wen, ZHANG
;
jian-ping, HUANG
- Publication Type:Journal Article
- Keywords:
antiphospholipid syndrome;
antiphospholipid body;
Henoch-Schonlein purpura
- From:Journal of Applied Clinical Pediatrics
2004;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Henoch-Schonlein purpura(HSP)is the most common vasculitic disease affecting children,which is a multisystem immunoglobulin A mediated vasculitis with a self-limited course affecting the skin,joints,gastrointestinal tract and kidneys.Antiphospholipid syndrome(APS)is a systemic autoimmune disorder characterized by a combination of arterial or venous thrombosis and recurrent fetal loss,accompanied by elevated titers of antiphospholipid antibodies.Both HSP and APS are multisytem diseases and are thought to result from immunologically mediated processes.It was known that APS can associated with HSP,but the relationship between the 2 diseases is unclear.The literature on HSP associated with APS was reviewed and the possible mechanism was analyzed.
