Regulation of Phosphatase and Tensin Homology Deleted on Chromosome 10
- VernacularTitle:第10号染色体缺失的磷酸酶与张力蛋白同源等位基因的调控机制
- Author:
tao, XIONG
;
de-yuan, LI
;
yi, QU
;
de-zhi, MU
- Publication Type:Journal Article
- Keywords:
phosphatase and tensin homologue deleted on chromosome 10;
regulation;
gene
- From:Journal of Applied Clinical Pediatrics
2004;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Phosphatase and tensin homology deleted on chromosome 10 (PTEN) is a tumor suppressor with dual protein and lipid phosphatase activity.PTEN is involved multisystem diseases and cancer,though the mechanisms of PTEN regulation are far from clear.Recent advances concerning regulation of PTEN including protein-protein interaction,phosphorylation,ubiquitination,oxidation and acetylation will be discussed.
