Central Nervous System Damage in Children with Mycoplasma Pneumoniae Pneumonia and Its Mechanism
- VernacularTitle:肺炎支原体肺炎患儿中枢神经系统损害及其机制
- Author:
Ai-lin, LIU
;
Li, LI
- Publication Type:Journal Article
- Keywords:
mycoplasma pneumoniae pneumonia;
central nervous system damage;
interleukin-18
- From:Journal of Applied Clinical Pediatrics
1992;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the central nervous system(CNS)damage in children with mycoplasma pneumoniae pneumonia(MPP)and explore its mechanism.Methods A total of 325 cases of MPP were selected to investigate the incidence of CNS damage,and the levels of IL-8,IL-18 and soluble interleukin-2 receptor(sIL-2R)in both serum and cerebrospinal fluid(CSF)were detected in those patients with CNS complications.Children with viral encephalitis at hospital during the same period were taken as control group.Use SPSS 12.0 software to analyze the data.Results There were 22 cases(6.8%)of MPP who had CNS complications,presented mainly with fever,vomiting,headache and convulsion.The levels of IL-8,IL-18 and sIL-2R were higher in MPP patients who had CNS complications than those in control group,especially the level of IL-18 and sIL-2R in CSF(Pa
