Early Diagnostic Value of N-Terminal Pro-B-Type Natriuretic Peptide for Heart Failure in Neonates
- VernacularTitle:N端脑钠肽前体对新生儿心力衰竭的早期诊断价值
- Author:
qian, ZHANG
;
cheng-han, LUO
;
jian, WANG
- Publication Type:Journal Article
- Keywords:
heart failure;
N-terminal pro-B-type natriuretic peptide;
early diagnosis;
infant,neonate
- From:Journal of Applied Clinical Pediatrics
1992;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the early diagnostic value of the expression level of plasma N-terminal pro-B-type natriuretic peptide(NT-proBNP)for heart failure(HF)in neonates.Methods Thirty-five neonates who were clinic diagnoses as HF newborns and 20 cases of non-HF newborns(control group)were selected,on the 2nd,the 7th day after birth,plasma NT-proBNP and CK-MB levels were measured with electrochemiluminescence method and mass method.All data were analyzed by SPSS 16.0 software.Results Compared with the control group,CK-MB and NT-proBNP were higher in the HF group before treatment(P0.05).Compared with before treatment,CK-MB and NT-proBNP were significantly lower in the HF group(P0.05),NT-proBNP level was lower in the control group(P