Analysis of Clinical and Pathological Characteristics and Prognosis in 21 Children with Primary Focal Segmental Glomerulosclerosis
- VernacularTitle:原发性局灶节段性肾小球硬化症患儿21例的临床、病理特点与预后分析
- Author:
shu, TENG
;
mo, WANG
- Publication Type:Journal Article
- Keywords:
primary focal segmental glomerulosclerosis;
pathology;
tubulointerstitial lesions;
prognosis;
child
- From:Journal of Applied Clinical Pediatrics
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).Two cases were lost to follow up,19 out of 21 cases were followed up.The follow-up duration was from 4 to 51 months[mean follow-up duration was(22.84?12.13) months].At last follow-up,10 cases(53%) had complete remission,4 cases(21%) had significant remission,4 cases(21%) had partial remission and 1 case(5%) had no remission.Tubulointerstitial lesions were related with prognosis(P1).Conclusions 1.The predominant clinical manifestation of primary FSGS is nephrotic syndrome in children.The not otherwise specified variant is the commonest pathological variant in primary FSGS.There is no relationship between patholo-gical types and clinical manifestations of FSGS.2.Most of the children with primary FSGS have a good short-term prognosis,but their long-term prognosis must be followed up.3.Tubulointerstitial lesions are risk factors for prognosis.
