Study Progress of Voltaged-Gated Sodium Channel Gene in Generalized Epilepsy with Febrile Seizures Plus
- VernacularTitle:全面性癫伴热性惊厥附加症电压门控钠离子通道基因的研究进展
- Author:
jian-hua, LI
;
jia-qin, WANG
;
xue-peng, GUO
- Publication Type:Journal Article
- Keywords:
generalized epilepsy with febrile seizures plus;
genetics;
voltaged-gated sodium channel gene
- From:Journal of Applied Clinical Pediatrics
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Generalized epilepsy with febrile seizures plus(GEFS+) is a new epilepsy syndrome proposed by International League Against Epilepsy.At present,the progress of genetic studies of GEFS+ focus on gene mapping based on family analysis,many researches indicate that GEFS+ is associated with voltaged-gated sodium channel(SCN) gene mutation.This paper intends to discuss the relationship beween GEFS+ and SCN1B,SCN2B,SCN1A,SCN2A genes,mutations in order to improve the cognition about GEFS+.
