Polyunsaturated Fatty Acids and Obesity
- VernacularTitle:多不饱和脂肪酸与肥胖
- Author:
jin, JIANG
;
ke-min, QI
- Publication Type:Journal Article
- Keywords:
obesity;
polyunsaturated fatty acids;
transcription factor;
leptin
- From:Journal of Applied Clinical Pediatrics
2006;0(19):-
- CountryChina
- Language:Chinese
-
Abstract:
Epidemiological and animal studies have demonstrated that dietary lower intake of n-3 polyunsaturated fatty acids (n-3 PUFAs) and(or) higher intake of n-6 polyunsaturated fatty acids(n-6 PUFAs) leading to imbalance of their ratios are closely related to obesity.The mechanisms underlied are involved in PUFA′s effects on fatty acid synthesis and oxidation,adipocyte proliferation and differentiation and leptin expression.At transcription level,PUFAs can regulate the activities of peroxisome proliferator-activated receptors and CCAAT enhancer bin-ding proteins.
