Expression of WT1 Gene in Acute Leukemia in Children and Its Clinical Significance
- VernacularTitle:WT1基因在急性白血病患儿中的表达及其临床意义
- Author:
xu-li, WANG
;
yi-huan, CHAI
;
shao-yan, HU
;
jian-nong, CEN
- Publication Type:Journal Article
- Keywords:
WT1 gene;
acute leukemia;
real-time quantitative reverse transcription polymerase chain reaction;
child
- From:Journal of Applied Clinical Pediatrics
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the expression of WT1 gene in acute leukemia in children and its clinical significance.Methods The real-time quantitative reverse transcription-polymerase chain reaction method was used to detect the expression level of WT1 gene in 198 children with acute leukemia.Results The medium of WT1 gene in children with acute leukemia was 932.99,but it was 38.50 in control group,and it in patient′s group was significantly higher than that in control group.The medium of WT1 gene in children with ALL was 195.73,while the medium of WT1 gene in children with acute myeloid leukemia was 6 297.75,and there was significant difference between the 2 groups(P
