Research Progress in Integrins and Angiogenesis
- VernacularTitle:整合素与血管生成的研究进展
- Author:
jing, ZHAO
;
yi, QU
;
de-zhi, MU
- Publication Type:Journal Article
- Keywords:
integrin;
angiogenesis;
endotheliocyte
- From:Journal of Applied Clinical Pediatrics
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Angiogenesis is a fundamental physiological and pathological process in human body.Angiogenesis is regulated by integrins,a family of cell surface receptors.After binding with their ligands such as extracellular matrix proteins and immunoglobulin superfamily molecules,integrins can promote the proliferation and migration of endothelial cells during angiogenesis.Several integrin-targeted therapeutic agents are currently used in clinical trials for the therapy of angiogenesis related diseases.Here,there will show the roles of integrins in angiogenesis and clinical application.
