Integrin-Linked Kinase and Integrin
- VernacularTitle:整合素连接激酶与整合素
- Author:
tao, XIONG
;
yi, QU
;
de-zhi, MU
- Publication Type:Journal Article
- Keywords:
integrin-linked kinase;
integrin;
signal pathway
- From:Journal of Applied Clinical Pediatrics
2006;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
Integrin is a kind of crucial adhesive molecule on the membrane,and it exerts its function through activating its intra-cellular effectors.One of the most important effectors is integrin-linked kinase (ILK),which is a serine/threonine protein kinase located in focal adhesions and has a key position in transducing many of the biochemical signals.It plays an important roles in regulating fundamental processes such as cell-matrix interactions,growth,proliferation,survival,differentiation,migration,invasion and angiogenesis under both physilogical and pathological processes.
