Critical Role of Toll-Like Receptors in Regulation of Immune Response
- VernacularTitle:Toll样受体在机体免疫应答中的调节作用
- Author:
li, MA
;
ya-ting, WANG
- Publication Type:Journal Article
- Keywords:
toll-like receptors;
signal transduction;
immune responses;
asthma
- From:Journal of Applied Clinical Pediatrics
2006;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
Toll-like receptors are an important pattern recognition receptors that recognize specific components of microbes and certain host molecules.Through initiated cell signaling pathway,they can induce immunocyte.Their activation triggers the innate immune response,and is crucial to the successful induction of Th1/Th2-phenotyped adaptive immunity.This review will give a brief overview of our current knowledge of TLRs as key components in immune responses and their regulation in respiratory tract diseases such as asthma.
