Significance of Serum Growth Hormone-Binding Protein Detection in Children with Idiopathic Short Stature
- VernacularTitle:特发性矮小症患儿生长激素结合蛋白测定的意义
- Author:
li, CHEN
;
sheng-xia, XIANG
;
xiao-qing, CHEN
;
ying-li, YANG
- Publication Type:Journal Article
- Keywords:
idiopathic short stature;
growth hormone;
growth hormone binding protein;
growth and development
- From:Journal of Applied Clinical Pediatrics
2006;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the change of growth hormone binding protein (GHBP) in children with idiopathic short stature(ISS).Methods Thirty children with ISS from the pediatric department in the Third Hospital of Hebei Medical University and 30 age-and sex-matched normal-stature children were selected from Sep.2006 to Jun.2008.The concentration of GHBP was measured by enzyme linked immunosordent assay.Results Serum GHBP levels in ISS subjects was (3 261.0?646.3) ?g/L,while the serum GHBP levels in normal control group was (2 026.0?497.2) ?g/L,and there was statistically significant difference between both groups(t=-20.67 P