Factors for Affecting Severity of Bronchiolitis in Children
- VernacularTitle:影响毛细支气管炎患儿临床严重程度的因素
- Author:
hua, DENG
;
zhou, FU
- Publication Type:Journal Article
- Keywords:
bronchiolitis;
risk factors;
obesity;
eczema
- From:Journal of Applied Clinical Pediatrics
2006;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the factors affecting severity of infants with bronchiolitis in hospital.Methods Data were collected from hospitalized case of bronchiolitis including age,gender,birth weight,incidence season,overweight,severity of bronchiolitis,clinical manifestation,pathogen,total and specific immunoglobulin-E (IgE),X-ray appearance,family asthma history,eczema,feeding patterns,congenital heart disease,countryside dwelling and length of stay.All cases were divided according severity extent into 2 groups.Then one-factor analytical method was used between 2 groups,and risk factors for these outcomes were identified by Logistic regression analysis.Results 1.Nearly 56%(506 of 904) of children were considered as obesity.2.The positive rate of the virus infection identified from 904 infants with bronc-hiolitis was 78.3%.Of them,the respiratory syncytial virus (RSV) infection accounted for 43.5%,cytomegalovirus (CMV) for 47.6%,coxsackie b virus (CBV) for 7.9%,Mycoplasma pneumonia (MP) for 1.8%,adenovirus (ADV) for 1.7% and epstein-barr virus (EBV) for 0.15%,respectively.3.There were notable differences between mild group and severe group in age,pathogen,birth weight,countryside dwel-ling,congenital heart disease and hospital day(?2=3.47,19.62,2.32,2.61,-4.71,69.23 P=0.001,0.006,0.02,0,0,0).There was a significant association between severe bronchiolitis and young age,low birth weight,congenital heart disease,countryside dwelling and hospital days (OR=0.840,0.542,15.412,5.305 and 1.173,respectively P=0.013 3,0.049 7,0.000 3,0,0.000 2).Conclusions 1.Obesity may have great risk for bronchiolitis.2.Except for RSV,CMV,CBV,ADV,MP and EBV all were pathogens associated with childhood bronc-hiolitis.3.The factors that contribute to increase risk of severe bronchiolitis are young age,low birth weight,congenital heart disease and countryside dwelling.And length of stay may estimate severity of infants with bronchiolitis in hospital.
