Effects of 3-Methlyadenine on Dynamic Expression of Cerebral Cortex Autophagy-Associated Protein Beclin1 in Newborn Rats with Recurrent Seizure
- VernacularTitle:3-甲基腺嘌呤对反复惊厥新生大鼠大脑皮层自噬相关蛋白Beclin1表达的影响
- Author:
yong, GONG
;
hong, NI
;
lu-yang, TAO
- Publication Type:Journal Article
- Keywords:
seizure;
Beclin1;
3-methlyadenine;
rat,newborn
- From:Journal of Applied Clinical Pediatrics
2006;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Conclusions Autop-hagy/lysosomal pathway was activated immediately after recurrent seizures as indicated by the elevated expression of Beclin1 in cerebral cortex. 3-MA was involved in the regulation of autophagy/lysosomal pathway by down-regulating the expression of Beclin1.
