Effects of L-Arginine on Bcl-2,Bax in Placenta and Blood Flow of Belly Stalk of Fetal Growth Restriction
- VernacularTitle:L-精氨酸对胎儿生长受限胎盘Bcl-2、Bax凋亡蛋白及脐动脉血流的影响
- Author:
su-fang, SHEN
;
cai-hong, HUA
;
qiu-yan, LUO
- Publication Type:Journal Article
- Keywords:
L-arginine;
fetal growth restriction;
Bcl-2;
Bax;
blood flow of belly stalk
- From:Journal of Applied Clinical Pediatrics
2006;0(14):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect and mechanism of L-arginine on fetal growth restriction by observing the expression of Bcl-2 and Bax in placenta.Methods Sixty patients with FGR were chosen,among which 30 cases who were treated with conventional ways were as convention group,and the other 30 cases who were treated with L-arginine were as L-arginine group.The birth weight and perinatal fetus outcome were detected.The central tissue of placenta got within 10 min after delivery were fixed by 100 g/L formaldehyde and embed by pa-raffin wax to observe the expression of Bcl-2 and Bax using immunohistochemistry.SPSS 11.5 software was used to analyze the data.Results Compared with convention group,the birth weight of L-arginine group was higher(P
