Gaseous Signal Molecules and Pathogenesis of Pulmonary Artery Hypertension
- VernacularTitle:气体信号分子与肺动脉高压的发病机制
- Author:
jing, DING
;
chao-mei, ZENG
;
jun-bao, DU
- Publication Type:Journal Article
- Keywords:
pulmonary artery hypertension;
gaseous signal molecules;
pathogenesis;
interaction;
nitric oxide;
carbon monoxide;
hydrogen sulfide;
sulfur dioxide
- From:Journal of Applied Clinical Pediatrics
2006;0(13):-
- CountryChina
- Language:Chinese
-
Abstract:
The 4 kinds of gaseous signal molecules——nitric oxide,carbon monoxide,hydrogen sulfide and sulfur dioxide,which were discovered by people consecutively,all played significant pathophysiological roles in the cardiovascular system.With the pathogenesis of pulmonary artery hypertension(PAH) being illuminated uninterruptedly,gaseous transmitters and the interaction between them become the hot issue in the domain.This article summarized the mechanism of gaseous signal molecules in the formation process of PAH,in order to identify that during the morbidity process of PAH gaseous transmitters took effect in network regulating model.It also possessed great significance to comprehend the pathophysiological variation of PAH profoundly.