Critical Antigenic Structure in Inducing Immune Damage of Peripheral Nerve Following Campylobacter Jejuni Infection
- VernacularTitle:空肠弯曲菌诱导外周神经传导阻滞的关键抗原结构
- Author:
xiao-hong, WANG
;
xiao-mei, SHU
;
bing-zhu, YANG
- Publication Type:Journal Article
- Keywords:
Campylobacter jejuni;
waaF mutant;
ganglioside;
nerve electrophysiology;
neuropathy
- From:Journal of Applied Clinical Pediatrics
2004;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).3.Thirty-three point three percent of animals from parental strain group were found fibrillations potentials and the po-sitive sharp waves in gastrocnemius electromyogram,no obvious abnormal waves were found in animals from both waaF mutant and control group.Conclusions The ganglioside-like epitope in LOS of CJ is critical antigen in inducing GM1-IgG antibody and in inducing conduction block of peripheral nerve,therefore,provide a support for the molecular mimicry theory as a pathogenesis in the axonal GBS following CJ infection.
