Infection,Inflammatory Response and Neonatal Brain Damage
- VernacularTitle:感染及炎性反应与新生儿脑损伤
- Author:
wen-li, LI
;
xiu-yong, CHENG
;
xiao-yang, WANG
- Publication Type:Journal Article
- Keywords:
infection;
inflammatory response;
brain damage;
lipopolysaccharide;
neonate
- From:Journal of Applied Clinical Pediatrics
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Infection and inflammatory response can induce the brain damage in neonate,but the mechanism involved in it has not been elucidated completely.Proposed mechanisms include inflammatory response,cytokine and free radical-mediated injury,and excitatory amino acids-induced injury.The activation of microglia and selective vulnerability of immature oligodendrocyte play an important role in the whole process.Recent researches show that the fetal inflammatory response and complex gene regulation are also involved in the infection-induced brain damage.
