Influence of Single and Multiple Course Dexamethasone on Brain Development of Preterm Infants
- VernacularTitle:产前应用单疗程及多疗程地塞米松对早产儿脑发育的影响
- Author:
li-juan, CHEN
;
xiu-yong, CHENG
- Publication Type:Journal Article
- Keywords:
dexamethasone;
brain development;
preterm infant
- From:Journal of Applied Clinical Pediatrics
1992;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of single and multiple course dexamethasone on brain development in preterm infants.Met-hods One hundred and eighteen preterm infants delivered after 28-34 weeks′ gestation from Aug.2005 to Mar.2007 in our NICU were enrolled in this study.These infants were divided into 3 groups by antenatalcourses of dexamethasone: control group,single-course group and multi-course group.Supportive treatments were given to all 3 groups.Neonatal behavioral neurological assessment(NBNA) was conducted on expected date of delivery.Mental and psychomotor developmental index was evaluated at 3,6,12 months by using intellectual development table made at Children′s Development Center of China(CDCC).Results The score of NBNA was much higher in single-course group than that in multi-course group and control group(Pa
