Study Progress of Haparanase in Kidney Diseases
- VernacularTitle:乙酰肝素酶在肾脏疾病中的研究进展
- Author:
zhi, ZHU
;
jian, YU
- Publication Type:Journal Article
- Keywords:
heparanase;
kidney disease;
proteinuria;
heparan sulfate proteoglycans
- From:Journal of Applied Clinical Pediatrics
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Heparanase(HPA) is an endo-beta-D-glucuronidase that degrades heparan sulfate proteoglycans side chains.Recently data suggested a role of HPA in several proteinuric diseases and an increased glomerular basement membrane.The research advanced of the molecular properties,the role in proteinuric diseases and the specific inhibitor of the human HPA were described.
