Adaptive Reaction of Actin Cytoskeleton in Podocyte Structure of Glomerulus
- VernacularTitle:肾小球足细胞骨架结构的适应性应变
- Author:
yu-lin, KANG
;
guang-hua, ZHU
;
wei-xun, HE
- Publication Type:Journal Article
- Keywords:
actin cytoskeleton in podocyte;
slit diaphragm;
RhoA/Rho kinase signal pathway;
p38MAP kinase
- From:Journal of Applied Clinical Pediatrics
1992;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Actin cytoskeleton in podocyte is a complicated network structure,and the stability of this structure depend on many proteins which located in slit diaphragm,the apical membrane domain and the basal membrane domain with the stimulus of mechanical stress,the actin cytoskeleton can be adaptive regulated to maintain the normal function of glomerulus,and several signal pathways involve in the process,such as RhoA/Rho kinase signal pathway and TRPC6.
