Meta-Analysis on Controlled Trials of Transcatheter Amplatzer Device Closure and Cardiac Surgery on Patent Ductus Arteriosus
- VernacularTitle:经导管Amplatzer封堵器和外科手术治疗动脉导管未闭对照试验的Meta分析
- Author:
juan, FENG
;
yu-lin, WANG
;
mei, ZHU
;
hao, LIANG
;
nan, ZHANG
;
wen-bin, GUO
- Publication Type:Journal Article
- Keywords:
patent ductus arteriosus;
transcatheter closure;
cardiac surgery;
Amplatzer device
- From:Journal of Applied Clinical Pediatrics
2006;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate the effectiveness of transcatheter Amplatzer device closure on patent ductus arteriosus(PDA),and to give some evidences for the clinical application.MethodsAll studies in the world regard to the controlled trials(CT) about transcatheter Amplatzer device closure and cardiac surgery on PDA were searched and made synthetic evaluation by means of Meta-analysis.RevMan 4.2.2 software was used for statistical analysis.Cases relative risk(RR)and its 95% confidence interval(CI)of procedure failure,the incidence of complication and residual shunt were calculated.ResultsTotally 5 studies including 349 cases were analyzed.Operation failure of Amplatzer device occlusion was higher than cardiac surgery [5 CT,349 cases,3.0% vs 0,RR=4.29,95%CI(0.77,23.95)](P=0.10).Incidence of complication of Amplatzer device occlusion was lower than cardiac surgery[5 CT,343 cases,3.1% vs 38.0%,RR=0.11,95%CI(0.05,0.23)](P
