Changes of Serum Adiponectin and Interleukin-6 in Neonates with Hypoxic-Ischemic Encephalopathy and Their Significances
- VernacularTitle:缺氧缺血性脑病新生儿血清脂联素、白细胞介素-6变化的意义
- Author:
ye, FENG
;
sheng-yun, SHI
;
xiao-yu, ZHOU
- Publication Type:Journal Article
- Keywords:
adiponectin;
interleukin-6;
hypoxic-ischemic encephalopathy;
infant,newborn
- From:Journal of Applied Clinical Pediatrics
2006;0(18):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationships between serum adiponectin,IL-6 and hypoxic-ischemic encephalopathy(HIE) degree in newborn infant.Methods Enzyme-linked immunoabsorbent assay was used to detect the serum adiponectin and IL-6 in 58 neonatal HIE and 26 neonates without HIE.And all the data were processed by SPSS 10.0 software.Results The level of serum adiponectin in moderate and severe HIE at acute stage were significantly lower than that of mild and control groups(Pa0.05).The level of serum IL-6 in moderate and severe HIE at acute stage were significantly higher than that of the mild and control groups(Pa0.05).The level of adiponectin were significant negative correlation with IL-6(r=-0.852 P
