Dynamic Changes of Coagulation and Fibrinolytic Function in Children with Systemic Inflammatory Response Syndrome
- VernacularTitle:全身炎性反应综合征患儿凝血与纤溶功能动态的变化
- Author:
yan-hong, LI
;
bin, LIU
;
xiao-dong, WANG
;
jian-hua, LIU
- Publication Type:Journal Article
- Keywords:
systemic inflammatory response syndrome;
platelet count;
antithrombase-Ⅲ;
D-dimer;
tissue plasm inogen activator;
activator of plasminogen inhibitor
- From:Journal of Applied Clinical Pediatrics
2006;0(18):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the dynamic changes of coagulation and fibrinolytic function in children with systemic inflammatory response syndrome(SIRS) and its clinical significance.Methods Seventy-two SIRS children were divided into mild group,severe group and dead group.Twenty healthy children were selected as control group in the same period.The intravenous blood samples were taken on 1,3 and 5 days after admission to measure PLT,plasma levels of antithrombase-Ⅲ(AT-Ⅲ),D-dimer(DD),tissue plasm inogen activator(t-PA)and plasm inogen activator inhibitor-1(PAI-1).Results On the first day,PLT were lower in severe and dead groups(Pa
