Study on stability of hormones in pig thyroid powder dried by different methods
- Author:
bung Ngoc Pham
- Publication Type:Journal Article
- Keywords:
Hormone
- MeSH:
Hormones;
Vacuum;
Thyroid Hormones;
Chromatography, Liquid
- From:Pharmaceutical Journal
2000;269(12):23-25
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
This study relates to stability of the hormones in the thyroid powder of the pig, dried by lyophilizating; vacuum drying at the temperature of 50oC, and by normal drying at the temperature 70oC. Using high performance liquid chromatography (HPLC) to measure thyroid hormone concentration in the powder of thyroid before and after release test at the temperature of 40±2oC and the relative humidity of 75±5% for 3 months. The result is: The hormone of the thyroid powder, dried at 70oC, have got required stability and it is less than the one of the thyroid powder dried by lyophilizating or vacuum drying.