Curative Effects of Monosialotetrahexosyl Ganglioside on Neonates with Moderate and Severe Hypoxic-Ischemic Encephalopathy
- VernacularTitle:单唾液酸四己糖神经节苷脂早期治疗中重度缺氧缺血性脑病新生儿的疗效
- Author:
ya-dong, LU
;
yong, LI
;
xiao-yu, ZHOU
;
xiao-ming, BEN
- Publication Type:Journal Article
- Keywords:
hypoxic-ischemic encepholopathy;
ganglioside;
infant,newborn
- From:Journal of Applied Clinical Pediatrics
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the curative effects of monosialotetrahexosyl ganglioside(GM1)on neonates with moderate and severe hypoxic-ischemic encephalopathy(HIE).Methods Eighty-six neonates with HIE were randomly divided into GM1 treatment group and control group.The control group(42 cases)were received routine treatment(including cerebrolysin and citicoline);the treatment group(44 cases)were given GM1 on the basis of routine treatment as early as possible(within 6 hours after birth).Brain CT,neonatal behavioral neurological assessment(NBNA)and children's development center of China(CDCC)at 12 months after birth were proformed in both groups.Results Brain CT,NBNA and CDCC markers in treatment group were better than those in control group(Pa
