Changes of S-100? and Glial Fibrillary Acidic Protein in Serum of Children with Epilepsy
- VernacularTitle:癫患儿血清S-100?、胶质纤维酸性蛋白变化的意义
- Author:
li, GAO
;
ying-xue, DING
;
yan-ping, LIU
;
xuan, ZHANG
;
juan, LIU
;
dong-ju, MA
- Publication Type:Journal Article
- Keywords:
S-100? protrein;
glial fibrillary acidic protein;
serum;
epilepsy;
child
- From:Journal of Applied Clinical Pediatrics
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the change of S-100? and glial fibrillary acidic protein(GFAP)in serum after seizure and medication in children with epilepsy.Methods Serum protein level of S-100? and GFAP were determined by double antibody sandwish enzyme-linked immunosorbent assay(ELISA)in 41 cases with epilepsy and 30 healthy children.The specimen of venous blood were taken by 24 hours after seizure,4 weeks,12 weeks after medicine and their supernate preserved at-80 ℃ after centrifugat.Results Twenty-four hours after seizure,protein level of S-100?,GFAP in serum was significantly higher than that of control group(Pa0.05).Four weeks after medication,protein level of S-100?,GFAP in serum of epileptic group decreased,but still higher than that in control group,and the difference was significant(P
