Relationship between Nitricoxide Synthase and Cell Apoptosis in Epilepsy
- VernacularTitle:癫癎发作过程中一氧化氮合酶与细胞凋亡的关系
- Author:
yue-ying, LIU
;
xing-qiang, DENG
;
zhuang-jian, XU
;
rui, LI
- Publication Type:Journal Article
- Keywords:
epilepsy;
cell apoptosis;
nitricoxide synthase
- From:Journal of Applied Clinical Pediatrics
2006;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship of nitricoxide synthase(NOS)and cell apoptosis in epilepsy.Methods Pentylenetetrazol(PTZ)was used to build models of epilepsy.Cell apoptosis in each group were detected by flow cytometer,level of NOS was detected by colorimetric method.Results Levels of NOS increased obviously 1 hour after epilepsy and decreased;but at the 6th hour,NOS increased again and peaked at the 24th hour.Cell apotosis begin to increase at 6th hour and peaked at 24th hour after epilepsy,and decreased at 48th hour after epilepsy,there were significance differences compared with control group(Pa
