Relationship between Serum Neopterin and D-Dimer Levels and Coronary Artery Dilatation in Kawasaki Disease
- VernacularTitle:血清新蝶呤、D-二聚体水平与川崎病冠状动脉扩张的关系
- Author:
guo-ming, NIE
;
min-shu, ZOU
;
jian, YU
- Publication Type:Journal Article
- Keywords:
neopterin;
D-dimer;
mucocutaneous lymph node syndrome;
child
- From:Journal of Applied Clinical Pediatrics
2006;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the levels of serum neopterin(NP) and D-dimer,and explore whether NP and D-dimer levels respond to coronary artery dilatation(CAD) of Kawasaki disease(KD),and evaluate the risk factors of CAD.Methods This study were conducted on 45 children with KD.Twenty-one children were CAD and 24 cases were not CAD.Active phase serum NP,D-dimer levels were measured by sensitive enzyme-linked immunosorbent assay(ELISA).Multiple regression analysis including platelet(PLT),monocyte(M),creatine kinase-MB(CK-MB),C-reactive protein(CRP),erythrocyte sedimentation rate(ESR),cardiac troponin I(cTnI) were studied with CAD.Results Compared with recovery phase,active phase the levels of PLT,M,CK-MB,CRP,ESR,cTnI were significantly higher(Pa
