Expression of Serum Interleukin-4,-6,-8 and Tumor Necrosis Factor-? in Children with Henoch-Schonlein Purpura
- VernacularTitle:过敏性紫癜患儿血清白细胞介素-4-、6-、8及肿瘤坏死因子-?表达的意义
- Author:
kai-li, PAN
;
qing-feng, BAI
;
ying, HUANG
;
qi, LI
- Publication Type:Journal Article
- Keywords:
Henoch-Schonlein purpura;
Henoch-Schonlein purpura nephritis;
interleukin-4;
interleukin-6;
interleukin-8;
tumor necrosis factor ?;
cytokine
- From:Journal of Applied Clinical Pediatrics
2006;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate changes of serum levels of interleukin(IL)-4,-6,-8 and tumor necrosis factor-?(TNF-?),and probe their clinical significance in children with Henoch-Schonlein purpura(HSP)/ HenochSchonlein purpura nephritis(HSPN).Methods Serum levels of IL-4,-6,-8 and TNF-? of 45 children with HSP/HSPN and 43 healthy children were examined by enzyme linked immunosorbent assay(ELISA),changes and correlation between the aforementioned cytokines in children with HSP /HSPN were analyzed.Results 1.Serum levels of IL-4,-6,-8 and TNF-? of children with HSP were higher than those of control group(P0.05);The serum level of TNF-? was positively correlated to the serum levels of IL-6,-8 of patients with HSP(r=0.670 P
