Significance of Expression of Serum Soluble Vascular Cell Adhesion Molecular and Soluble Intercellular Molecule-1 in Children with Henoch-Schoenlein Purpura
- VernacularTitle:过敏性紫癜患儿血清可溶性血管细胞黏附分子-1及可溶性细胞间黏附分子-1表达的意义
- Author:
yong, GU
;
guo-cheng, XU
;
shuang-gen, MAO
- Publication Type:Journal Article
- Keywords:
Henoch-Schoenlein purpura;
soluble vascular cell adhesion molecular-1;
soluble intercellular molecule-1
- From:Journal of Applied Clinical Pediatrics
2006;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect the levels of plasma soluble vascular cell adhesion molecular(sVCAM-1) and soluble intercellular mo-lecule-1(sICAM-1) in children with Henoch-Schoenlein purpura(HSP) and its clinical significance.Methods The plasma levels of sVCAM-1 and sICAM-1 were measured by enzyme-linked immunosorbent assay(ELISA) in 53 children with HSP(37 cases in acute stage and 16 cases in recovery stage)and in 25 healthy subjects respectively,and the change that in acute stage and recovery stage was analyzed,at the same time,the 2 factors in children with renal injury and without injury were analyzed.Results The serum levels of sVCAM-1 and sICAM-1 in acute stage HSP children were significantly higher than those in recovery stage and normal controls(Pa
