Cytokine Imbalance and Its Function in Morbidity of Autoimmune Thyroid Disease in Children
- VernacularTitle:自身免疫甲状腺病患儿细胞因子的失衡及其在发病中的作用
- Author:
yu, YANG
;
li-ling, XIE
;
jiang-wei, KE
;
li, YANG
- Publication Type:Journal Article
- Keywords:
thyroiditis,autoimmune;
cytokines;
child
- From:Journal of Applied Clinical Pediatrics
2006;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of cytokine levels and their roles in morbidity of autoimmune thyroid disease(AITD) in children.Methods The serum concentrations of interleukin-4(IL-4),interleukin-6(IL-6),tumor necrosis factor-?(TNF-?),interferon-? (IFN-?) were determined with enzyme linked immunosorbent assay (ELISA) among 30 patients with Graves′ disease (GD) and 20 patients with Hashimotos thyroiditis(HT) and 30 children without AITD subjects.Results The serum levels of IL-4 and IL-6 in patients with GD were higher than those of subjects (Pa
