Expression of Adiponectin Receptor 2 in Diet-Induced Obese Rat′s Liver
- VernacularTitle:脂联素受体2基因在饮食诱导肥胖大鼠肝脏组织中的表达
- Author:
yong-sheng, ZHU
;
feng, LIU
;
xi-rong, GUO
- Publication Type:Journal Article
- Keywords:
adiponectin receptor 2;
obesity;
insulin sensitivity;
rats
- From:Journal of Applied Clinical Pediatrics
2006;0(19):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the different expressions of adiponectin receptor 2(AdipoR2) mRNA in liver between diet-induced obese rats and controls.Methods The level of AdipoR2 mRNA expression was detected by reverse transcriptase polymerase chain reaction(RT-PCR).Insulin sensitivity was evaluated by insulin sensitivity index(ISI).Results Diet-induced obese rats showed higher expression of AdipoR2 mRNA compare to controls.The ISI of diet-induced obese rats was lower than that of controls.Conclusion High energy diet induceds AdipoR2 expression in liver.
