Relative Factors of Neonatal Necrotizing Enterocolitis and Preventive Effect of Microeco-Preparation
- VernacularTitle:坏死性小肠结肠炎早产儿病因及微生态制剂预防作用
- Author:
xiao-yuan, ZHUANG
;
lian-qiao, LI
;
xuan-xuan, GAO
;
li-duan, SU
- Publication Type:Journal Article
- Keywords:
enterocolitis,necrotizing;
infant,newborn;
relative factors;
probiotics
- From:Journal of Applied Clinical Pediatrics
2006;0(18):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the risk factors of neonatal necrotizing enterocolitis(NEC)and assess the effect of prophylactic use of probiotics(Bifico)in prevention of NEC and observe changes of weight.Methods Five hundred and twenty-four cases of prematures who were inpatients were divided into 2 groups randomly(prevention group,n=276,no-prevention group,n=248)and the morbidity of NEC and the increase of eight during hospitalization were observed.A case-control study and conditional Logistic regression model multifactorial analysis were made to 20 cases NEC neonates and 80 cases non-NEC neonates.Results The prevention group(276 cases)had 5 cases of NEC and the average weight increase was(8.114?8.137)g/d,the no-prevention group 248 cases had 17 cases of NEC,and the average weight increase was(6.595?5.337)g/d.The occure rate of NEC in prevention group was significantly lower than that of no-prevention group(?2=5.57 P
