Factors of Serumal Estrogen Increasing in Infant with Hemangiomas and Its Relationship with Tumors' Proliferation
- VernacularTitle:血管瘤患儿雌激素升高因素及其与瘤体增生的关系
- Author:
wei-li, XU
;
chun-feng, DONG
;
ai-guo, NIU
;
suo-lin, LI
- Publication Type:Journal Article
- Keywords:
hemangioma;
estradiol;
estrogen;
receptor
- From:Journal of Applied Clinical Pediatrics
2006;0(18):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the factors of high level of serum estradiol(E2)in infant with hemangiomas and its relationship with tumors' proliferation.Methods The levels of serumal estradiol of 25 proliferative hemangiomas and 15 oblique inguinal hernias with same ages 1 day preoperation and 3 days postoperation were tested by chemiluminescence enzymatic immune method.The expressions of estrogen receptors(ER)in 25 tumors and 15 normal skin tissue were tested by immunohistochemical method.Results The levels of E2 of preoperation were ob-viously higher than that of postoperation in hemangiomas and control group(Pa0.05).The expression of ER in tumors was significantly higher than that in normal skin tissue(P
