Relationship between Expression of Respiratory Viruses from Urine in Children with Steroid Responsive Simple Nephrotic Syndrome and Its Episode
- VernacularTitle:激素敏感型单纯性肾病综合征患儿尿液呼吸道病毒表达及其与发病的相关性
- Author:
jin, WU
;
zheng, WANG
;
yu-hong, TAO
- Publication Type:Journal Article
- Keywords:
nephrotic syndrome;
respiratory virus;
heparan sulfate;
urine
- From:Journal of Applied Clinical Pediatrics
2006;0(17):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between respiratory viruses infection and the episode of steroid responsive simple nephrotic syndrome(SRSNS).Methods Thirty-eight children with SRSNS were selected,including the active stage group(n=28)and the remission group(n=10).The urine from 18 cases of nephritic nephrosis,16 cases of bronchiolitis,15 cases of secondary glomerular diseases and 15 cases of healthy children were served as controls.By using the method of reverse transcriptase-polymerase chain reaction(RT-PCR)and alkaline phosphoesterase-anti alkaline phosphoesterase enzyme-linked assay(APAAP),viral genes and antigens in urine were assayed,respectively.Results The positive rate of detecting viruses in the active stage group of SRSNS children was higher than that in the remission group and the other control groups(Pa
