Changes of Levels of Serum Intereferon-? and Interleukin-4 in Children with Mycoplasma Pneumoniae Encephalitis
- VernacularTitle:肺炎支原体脑炎患儿血清细胞因子干扰素-?、白细胞介素-4的变化
- Author:
zhong, XU
;
bai-hong, ZHENG
;
min, XU
;
xin, TIAN
- Publication Type:Journal Article
- Keywords:
mycoplasma pneumoniae;
encephalitis;
intereferon-?;
interleukin-4
- From:Journal of Applied Clinical Pediatrics
2006;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of intereferon-?(IFN-?)and interleukin-4(IL-4)in peripheral blood of children with mycoplasma pneumoniae(MP) encephalitis at the acute phase.Methods The peripheral blood concentrations of IFN-? and IL-4 were measured by enzyme-linked immunosorbent assay(ELISA) in 24 cases of children with MP encephalitis at the acute stage.The samples from 24 cases of healthy children were control group.Twenty-four children with MP encephalitis were intravenous drip with azithromycin,at the same time,10 cases received hexadecadrol and 15 cases received gamma globulin.Results The serum concentrations of IFN-? and IL-4 in the mycoplasmal encephalitis group were(98.56?12.93) and(45.55?17.58) ng/L,respectively,which were significantly higher than those in control group [(85.35?6.91) and(26.78?9.89) ng/L] respectively(Pa
