Genetic Research of Gene of Gamma 2 Subunit of Gamma-Aminobutyric Acid Type A Receptor in Pedigrees of Generalized Epilepsy with Febrile Seizures Plus
- VernacularTitle:全面性癫癎伴热性惊厥附加症家系?-氨基丁酸A型受体?2亚单位基因研究
- Author:
xiu-hong, CHANG
;
xi-shun, HUANG
;
jian-ke, WEI
- Publication Type:Journal Article
- Keywords:
generalized epilepsy with febrile seizures;
gamma 2 subunit of gamma-aminobutyric acid type A receptor;
child
- From:Journal of Applied Clinical Pediatrics
2006;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To find the relationship between mutation of gamma 2 subunit of the gamma-aminobatyric acid type A receptor(GABRG2) and generalized epilepsy with febrile seizure plus(GEFS+).Methods Probands of 10 families with GEFS+ were selected,the GABRG2 gene were sequenced.Results We found a single nucleotide polymorphism site,and did not find the reported mutations.Conclusion GABRG2 mutation is not common in Hans of northern China.
