Significance of Changes of Tumor Necrosis Factor-? and Interleukin-6 Level in Children with Acute Viral Myocarditis
- VernacularTitle:急性病毒性心肌炎患儿血清肿瘤坏死因子-?、白细胞介素-6水平变化的意义
- Author:
yan, LI
;
wen-ping, ZHOU
;
bin, LUAN
- Publication Type:Journal Article
- Keywords:
myocarditis,acute,viral;
tumor necrosis factor-?;
interleukin-6
- From:Journal of Applied Clinical Pediatrics
2006;0(13):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical significance and changes of tumor necrosis factor-?(TNF-?)and interleukin-6(IL-6)level in children with acute viral myocarditis(AVM).Methods TNF-? and IL-6 level in serum from 53 AVM children and 20 healthy children were measured by radio-immunoassay and enzyme-linked immunosorbent assay(ELISA).The relation between the levels of TNF-? and IL-6 in serum with the occurrence and development in acute viral myocarditis was analyzed.Results Thirty-two were males and 21 females in the 53 AVM children.The ages ranged from 3-11 years old.There were 12 males and 8 females in control group.The serum level of TNF-? and IL-6 were(526.7?32.9),(3.23?0.53)mg/L in AVM group and(383.1?27.5),(1.63?0.22)mg/L in control group.There were significant difference between the 2 groups(Pa
