Expression of Inhibitor of Apoptosis Protein Livin in Children with Acute Lymphocytic Leukemia
- VernacularTitle:Livin蛋白在急性淋巴细胞白血病儿童中的表达
- Author:
qun-li, HE
;
li-qun, MIAO
;
guo-xin, ZHAO
;
bin, GUO
;
xiang, SUN
;
yong-ling, WANG
;
guo-qiang, ZHAO
- Publication Type:Journal Article
- Keywords:
Livin;
inhibitor of apoptosis protein;
acute lymphocytic leukemia;
immunohistochemistry
- From:Journal of Applied Clinical Pediatrics
2006;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expression of Livin,a novel inhibitor of apoptosis protein(IAP)family member in children with acute lymphocytic leukemia(ALL).Methods Livin protein of 40 cases myeloid tissue of children with ALL and 20 cases that of non-leukemia children were assayed by streptomycin avidin-biotin-peroxidase complex staining immunohistochemical method in order to analyze the relationship between Livin protein expression and development of ALL.Results The positive rates of Livin protein expression was 40% in 40 cases ALL,but in control group,the positive rates of Livin protein expression was 5%.The difference of 2 groups was significant(P
