Relationships between Plasma Vasoactive Intestinal Peptide,Superoxide Dismutase,Malondialdehyde and Brain Damage in Neonates with Asphyxia
- VernacularTitle:窒息新生儿血浆血管活性肠肽、超氧化物歧化酶、丙二醛水平与脑损伤的关系
- Author:
bao-qin, LIU
;
hong, XIONG
;
qun-si, WANG
- Publication Type:Journal Article
- Keywords:
asphyxia;
vasoactive intestinal peptide;
superoxide dismutase;
malondialdehyde;
infant,newborn
- From:Journal of Applied Clinical Pediatrics
2006;0(14):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationships between plasma vasoactive intestinal peptide(VIP),superoxide dismutase(SOD),malondialdehyde(MDA) and hypoxic-ischemic brain damage(HIBD) in neonates with asphyxia.Methods Sixty-eight full-term neonates hospitalized with asphyxia were enrolled in this study (simple asphyxia group 15 cases,mild HIE group 17 cases,moderate HIE group 22 cases and severe HIE group 14 cases) according to the diagnostic criteria of neonatal hypoxic- ischemic encephalopathy(HIE),and 20 cases in control group.Plasma VIP,SOD and MDA were detected by radio-immuhoassay,thiobarbatic acid colorimety and xanthine oxidase at d1 and d7 after born in every group.Results 1.There were significant difference in the plasma VIP,SOD and MDA among every group(Pa
