Changes of Soluble Tumor Necrosis Factor-? Receptor Type 1 in Cerebrospinal Fluid of Children with Virus Encephalitis and Its Clinical Significance
- VernacularTitle:病毒性脑炎患儿脑脊液可溶性肿瘤坏死因子受体1的变化及临床意义
- Author:
hong-yan, CHEN
;
qiu-ye, ZHANG
;
zhi-rong, SHU
;
yu-zong, NIU
;
wen-di, WANG
- Publication Type:Journal Article
- Keywords:
viral encephalitis;
child;
cerebrospinal fluid;
tumor necrosis factor-?;
tumor necrosis factor-? receptor
- From:Journal of Applied Clinical Pediatrics
2004;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of soluble tumor necrosis factor receptor type 1(sTNFR1)in children with acute virus encephalitis(VE)and its clinical significance.Methods The levels of tumor necrosis factor-?(TNF-?),sTNFR1 and neuron specific enolase(NSE)in cerebrospinal fluid were determined by enzyme-linked immunosorbent assay(ELISA)in 55 children who were admitted with VE,including 25 cases with severe VE(SVE)and 30 cases with mild VE(MVE).Fifteen cases without VE were as control group.Results The levels of TNF-?,sTNFR1 in cerebrospinal fluid in encephalitis children were significantly higher than that in control group(Pa
