Effect of Gramsetron Combined with Dexamethasone on Preventing Postoperative Nausea and Vomiting after One-trocar Laparoscopic Appendectomy in Children
- VernacularTitle:格拉司琼联合地塞米松预防小儿单孔法腹腔镜阑尾切除术后恶心呕吐
- Author:
jun, CHAI
;
xiu-ying, WU
;
wei-min, CHEN
- Publication Type:Journal Article
- Keywords:
gramsetron;
dexamethesone;
appendectomy,laparoscopic;
postoperative nausea and vomiting;
child
- From:Journal of Applied Clinical Pediatrics
2004;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy of prophylactic use of gramsetron(Gra) combined with dexamethasone(DEX) on preventing postoperative nausea and vomiting(PONV) after umbilical one-trocar laparoscopic appendectomy(UOTLA)in children.Methods Sixty children requring UOTLA under general anesthesia were allocated randomly into 3 groups,and each of group included 20 children.Group saline(C),group Gra 40 ?g/kg,group Gra 40 mg/kg and group DEX 0.2 mg/kg(Gra+DEX) were respectively injected intravenously after appendectomy performed outside the abdominal cavity during the operation.Results The incidence of PONV decreased significantly in group Gra and group Gra+DEX than that in group C(Pa
